24ADVERSE DRUG REACTION AND PHARMACOVIGILANCE- AN OVERVIEWAdverse drug reaction by WHO ―a response to a drug which is noxious and unintended, and which occurs at doses normally used in man for the prophylaxis, diagnosis, therapy of disease, or for the modification of physiological functions. Whereas, pharmacovigiliance as the science and activities related to the detection, assessment, understanding and prevention of adverse effects or any other drug related problem. It warn‘s us and helps us in withdrawl of an offending pharmaceutical product. Our review article mainly focuses on the role of adverse drug reaction and pharmacovigiliance. We developed a search strategy to find publications about ADR and its management. So, we searched Science Direct, Medline and PubMed bibliographic databases using the key phrases causes of ADR, PV, and drugs under suspected unwanted reaction. Our review article suggests that, drug related problem in the community as well as in hospital increased in both developing and developed countries. Hence awareness should create among the public regarding proper usage of drugs and strengthen the pharmacovigilance program in every country.vijayvijay66@yahoo.co.inReview312013Drugs,Community,Hospital,Gender,Pharmacovigliance and IndiaVijayakumar SubashAssociate Professor, Department of Pharmacy Practice, Vaagdevi College of Pharmacy, MGM Hospital, Warangal, Andhra Pradesh, India.