178ANTI-ARTHRITIS ACTIVITY OF Solanum Nigrum IN EXPERIMENTAL ANIMAL MODELSThe aim of this study was to assess the anti-arthritic activity of Solanum nigrum. Arthritis is induced in the albino rats by inducing the freunds complete adjuvant. The seeds of freunds adjuvant were coarsely powdered and extracted with ethanol (95%) and water using soxhlet. The effect of these plant extracts on arthritic rats were assessed by the various blood parameters and also taking the changes in paw volume. The SN suppressed the anti arthritic changes induced in rats and results were statically significantshekar9849raju@yahoo.comResearch922019Solanum nigrum,Anti-arthritic activity, Seed extractK. Raja Sheker, A. Anil kumar,G. Abhilash,B. Naveen,C.R. AkilaDepartment of Pharmaceutical Sciences, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India,Department of Pharmaceutical Sciences, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India,Department of Pharmaceutical Sciences, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India,Department of Pharmaceutical Sciences, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India,Department of Pharmaceutical Sciences, Scient Institute of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India