131PRESCRIPTION PATTERN ANALYSIS OF ANTI-DIABETIC DRUGS IN A TERTIARY CARE HOSPITAL OF INDIADiabetes mellitus [DM] is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Type 2 DM (formerly known as non-insulin dependent DM) is the most common form of DM characterized by hyperglycemia, insulin resistance, and relative insulin deficiency. People living with type 2 DM are more vulnerable to various forms of both short- and long-term complications, which often lead to their premature death. Concurrent illness such as hypertension in diabetics makes it more difficult to avoid multiple drug use; hence diabetics are more prone to polypharmacy and sometimes to irrational prescriptions.This study is therefore aimed at determining the pattern of drug prescription among type 2 diabetic patients. To analyze prescription pattern of anti-diabetic drugs for patients with type 2 diabetes alone and with coexisting diseases. A descriptive cross sectional study was carried out in 238 out patients for a period of 3 months in a tertiary care hospital. Patients treated with anti-diabetic agents were used for the study. The demographic data, disease data and utilization of different classes of anti-diabetic agents as well as individual drugs were analyzed. Out of the 238 patients enrolled in the study, 112 (47.06%) were males and 126(52.94%) were females. Among the study population, 117 (49.16%) suffering from diabetes alone and 121 (50.84%) suffering from diabetes with hypertension. Out of the total, 71 patients (29.83%) were on mono therapy, 124 patients (52.10%) were on dual therapy, 41 patients (17.23%) were on triple therapy and 2(0.84%) were on four drug therapy. Among 213 antidiabetic drugs prescribed in diabetic patients without hypertension, 100 patients (46.95%) were prescribed with Metformin, 65 patients (30.52%) with Glimepiride, 35 patients (16.43%) with Insulin. Among 240 antidiabetic drugs prescribed in diabetic patients with hypertension, 109 patients (45.42%) were prescribed with Metformin, 78 patients (32.50%) with Glimepiride, 32 patients (13.33%) with Insulin .In this study females were found to be more affected by Type-2 Diabetes mellitus than males. Elderly patients were at higher risk of developing Type-2 Diabetes. In this study it was found that combination therapy was more used than monotherapy. Sulfonylurea and Biguanide combination drugs were commonly used. In these Glimepiride and Metformin combination drugs were used commonly.dradake82@gmail.comResearch722017Type-2 Diabetes Mellitus,Prescription Pattern,Dual Therapy,MetforminNagapati Prabhakar Bhat,Prabhakar Adake,Roopa P NayakAssistant Professor, Department of Pharmacology, Yenepoya Medical College, Yenepoya University, Mangalore-575018.,Assistant Professor, Department of Pharmacology, Yenepoya Medical College, Yenepoya University, Mangalore-575018.,Assistant Professor, Department of Pharmacology, Yenepoya Medical College, Yenepoya University, Mangalore-575018.