122A STUDY OF PRESCRIPTION PATTERN IN THE DRUG THERAPY OF FEMALE REPRODUCTIVE TRACT INFECTIONSFemale Reproductive tract infections (FRTIs) are being increasingly recognized as a serious global health problem with impact on individual women, their families and communities. Although a handful of studies have shown that monotherapies for FRTIs achieve high rates of clinical cure, the efficacy of these regimens in preventing adverse reproductive sequelae is not fully elucidated. This prospective study envisages compilation, analysis of the pattern, trend, rationality and frequency of the use of drugs in the treatment of FRTIs, with emphasis on available treatment regimens inclusive of primary and adjunctive therapy. The average number of AMAs per prescription was 3.1±1.25. Polytherapy was observed in 92.7% of the prescriptions. Among the infections reported the most common was chronic PID (29.5%) followed by Acute PID(23.4%), cervicitis(13.1%), vaginitis (13.1%), vulvitis(10.6%), endometritis (6.3%), vulvovaginitis (3.3%) and pyosalpinx (0.7%). In a total of 397 patients, culture and sensitivity tests were performed in 148 patients and micro-organism isolates were seen in 129 cases. The notable microbes isolated were CONS (23.6%), candida (18.3%), bacterial vaginosis (16.3%), E.coli (11.5%), others (8.8%) and staphylococcus aureus (4.7%). Among AMAs, anti-parasitic agents (34.3%) were most commonly prescribed, followed by cephalosporins (29.5%), anti-fungals (11.7%), tetracyclines (11.5%), aminoglycosides (7.4%), fluoroquinolones (4%) and others (1.6%). The first 5 AMAs form DU90% segment. In the adjunctive therapy, analgesics (23.2%), GPAs (22.7%), nutrients (19.2%), anti-emetics (14.3%), and anti-histamines (8.8%) were prescribed. There was significant association observed between the nature of disease and type of treatment.drrajeshb83@gmail.comReview622016FRTIs,PID,DU90,Prescription patternAmeena Khatoon Koralli,Rajesh B,S Vijayaraghavan,Kokila BN Senior Pharmacovigilance Physician, Quintiles India Pvt Ltd, Bangalore, Karnataka, India,Assistant Professor, Department of Pharmacology, Shridevi Institute of Medical Sciences & Research Hospital, Tumkur, Karnataka, India.,Department of Pharmacology, K.V.G. Medical College & Hospital, Sullia, Karnataka, India,Department of Pharmacology, K.V.G. Medical College & Hospital, Sullia, Karnataka, India